As profile of bombing suspects emerges, uncle says: ‘We’re ashamed’ Boston on lock-down.

One suspect in the Boston Marathon bombings is dead. The other — his brother — was on the run Friday, pursued by an army of law enforcement officials whose manhunt virtually shut down the city.

A man identified by several sources as Tamerlan Tsarnaev, 26, died after an overnight shootout with police. He’s the man described Thursday by the FBI as black-capped Suspect No. 1 in the attacks Monday that killed three.

His brother, Dzhokar Tsarnaev, apparently escaped — leading police to throw a huge dragnet around the region. In photos released by the FBI of the bombing suspects, the younger brother is seen wearing a white cap. The agency called him Suspect No. 2.

Developments moved quickly: Here is a partial timeline.